Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)- synthesis
- Product Name:Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)-
- CAS Number:932706-21-3
- Molecular formula:C5H11ClFN
- Molecular Weight:139.5989
932706-26-8
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932706-21-3
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Yield:-
Reaction Conditions:
Stage #1:benzyl [(1S,3R)-3-fluorocyclopentyl]carbamate with hydrogen;palladium hydroxide on carbon in methanol at 20; under 759.826 Torr; for 20 h;
Stage #2: with hydrogenchloride in 1,4-dioxane
References:
BANYU PHARMACEUTICAL CO., LTD. WO2007/37513, 2007, A1 Location in patent:Page/Page column 45-46