ETHYL 1-(4-CHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLATE synthesis

2synthesis methods

Product Name:ETHYL 1-(4-CHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLATE
CAS Number:91396-27-9
Molecular formula:C12H12ClN3O2
Molecular Weight:265.7

106-47-8 Synthesis

106-47-8
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$5.00/5G

ETHYL 1-(4-CHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLATE

91396-27-9
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Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / methanol; water / 0.25 h / 0 °C
1.2: 12 h / 0 - 20 °C / pH 5
2.1: toluene / 2 h / Reflux

References:

Liu, Shu;Premnath, Padmavathy Nandha;Bolger, Joshua K.;Perkins, Tracy L.;Kirkland, Lindsay O.;Kontopidis, George;McInnes, Campbell [Journal of Medicinal Chemistry,2013,vol. 56,# 4,p. 1573 - 1582]

107-29-9
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$9.00/1g

ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE

27143-09-5
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$50.00/10mg

91396-27-9
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References