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ChemicalBook CAS DataBase List 6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER
885280-00-2

6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 97 percent / H2NNH2; FeCl3*6H2O / methanol
2: 62 percent / aq. 5 percent AcOH
3: 90 percent / methanol / 67 °C

References:

Young, Jonathan R.;Huang, Song X.;Walsh, Thomas F.;Wyvratt Jr., Matthew J.;Yang, Yi Tien;Yudkovitz, Joel B.;Cui, Jisong;Mount, George R.;Ren, Rena Ning;Wu, Tsuei-Ju;Shen, Xiaolan;Lyons, Kathryn A.;Mao, An-Hua;Carlin, Josephine R.;Karanam, Bindhu V.;Vincent, Stella H.;Cheng, Kang;Goulet, Mark T. [Bioorganic and Medicinal Chemistry Letters,2002,vol. 12,# 5,p. 827 - 832]

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