
4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro-, radical ion(1+), (3aα,4β,7β,7aα)- (9CI) synthesis
5synthesis methods
- Product Name:4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro-, radical ion(1+), (3aα,4β,7β,7aα)- (9CI)
- CAS Number:85081-16-9
- Molecular formula:C9H8O3
- Molecular Weight:164.16
Yield:85081-16-9 96.1%
Reaction Conditions:
in ethyl acetate at -10;Temperature;
Steps:
1-4 Example 1
98.00 g (1.00 mol) of maleic anhydride was placed in the reactor,Add 300.00 g of ethyl acetate to dissolve,72.71 g (1.10 mol) of cyclopentadiene was slowly added dropwise at low temperature.Control the reaction temperature -10 ° C,The white crystals are continuously precipitated during the reaction.After the addition of cyclopentadiene is completed, the reaction is completed.Filtration and vacuum drying gave 157.60 g of white solid, yield 96.10%.
References:
CN109627252,2019,A Location in patent:Paragraph 0005; 0020-0021; 0025-0026; 0030-0031; 0035-0036