6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL synthesis

5synthesis methods

Product Name:6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL
CAS Number:81864-47-3
Molecular formula:C9H8N2O2S
Molecular Weight:208.24

81927-47-1 Synthesis

81927-47-1
30 suppliers
$45.00/10mg

140-89-6
300 suppliers
$12.00/5g

6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL

81864-47-3
23 suppliers
$130.00/50mg

Yield:81864-47-3 69%

Reaction Conditions:

in methanol; for 5 h;

Steps:

6.5

Step 5: 7-mercapto-6H-2,3-dihydro[1,4]dioxino[2,3-f]benzo[d]imidazole [Show Image] The production obtained in the Step 4 (5 g, 30 mmol) was dissolved in anhydrous methanol (300 mL). Potassium ethylxanthate (7.1 g, 45 mmol) was added, stirred for 5 h. The solvent was removed, water and concentrated hydrochloric acid were added, and the reaction mixture was adjusted to pH 3, and extracted with ethyl acetate. The organic layers were combined and then washed with water and saline, dried, concentrated under vacuum to obtain a product (4.3 g, 69%).

References:

EP2532665,2012,A1 Location in patent:Page/Page column 30

63546-19-0 Synthesis