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ChemicalBook CAS DataBase List [5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one
76375-62-7

[5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one synthesis

2synthesis methods
17398-00-4 Synthesis
aspyrone

17398-00-4
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2H-Pyran-2-one, 3-[(1S,2S)-2-chloro-1-hydroxypropyl]-5,6-dihydro-5-hydroxy-6-methyl-, (5S,6R)-

1043452-75-0
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2H-Pyran-2-one, 3-[(1R,2S)-1-chloro-2-hydroxypropyl]-5,6-dihydro-5-hydroxy-6-methyl-, (5S,6R)-

1043452-74-9
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Yield:1043452-74-9 2.0 mg ,76375-62-7 1.0 mg

Reaction Conditions:

with hydrogenchloride in chloroform;water at 0; for 0.5 h;

References:

Zhang, Dahai;Yang, Xiudong;Jung, Sook Kang;Hong, Dae Choi;Byeng, Wha Son [Journal of Natural Products,2008,vol. 71,# 8,p. 1458 - 1460] Location in patent:experimental part

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