7-chloro-1-Methyl-1H-pyrazolo[3,4-c]pyridine synthesis

1synthesis methods

Product Name:7-chloro-1-Methyl-1H-pyrazolo[3,4-c]pyridine
CAS Number:957760-15-5
Molecular formula:C7H6ClN3
Molecular Weight:167.6

76006-11-6 Synthesis

76006-11-6
107 suppliers
$13.00/100mg

74-88-4
351 suppliers
$15.00/10g

1373333-62-0 Synthesis

7-chloro-2-Methyl-2H-pyrazolo[3,4-c]pyridine

1373333-62-0
34 suppliers
$230.00/250mg

7-chloro-1-Methyl-1H-pyrazolo[3,4-c]pyridine

957760-15-5
40 suppliers
$84.00/100mg

Yield:1373333-62-0 63% ，957760-15-5 24%

Reaction Conditions:

Stage #1: 7-chloro-1H-pyrazolo<3,4-c>pyridinewith sodium hydride in tetrahydrofuran at 0;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran at 0 - 20;Inert atmosphere;

References:

Zhang, Yan;Ye, Wei;Wang, Haisheng;Schneller, Stewart W. [Synthesis,2012,vol. 44,# 5,p. 723 - 730] Location in patent:experimental part