6-Fluoro-1H-indole-4-carboxylic acid methyl ester synthesis
- Product Name:6-Fluoro-1H-indole-4-carboxylic acid methyl ester
- CAS Number:1082040-43-4
- Molecular formula:C10H8FNO2
- Molecular Weight:193.17
33184-16-6
323 suppliers
$6.00/1g
1082040-43-4
212 suppliers
$26.00/100mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: sulfuric acid; nitric acid / water / 0.5 h / 0 - 5 °C / Large scale
2.1: sulfuric acid; nitric acid / water / 24 h / 65 °C / Large scale
3.1: triethylamine / N,N-dimethyl-formamide / 4 h / 95 - 100 °C / Large scale
3.2: 4 h / 30 °C / Large scale
References:
Gillmore, Adam T.;Badland, Matthew;Crook, Clare L.;Castro, Nieves M.;Critcher, Douglas J.;Fussell, Steven J.;Jones, Katherine J.;Jones, Matthew C.;Kougoulos, Eleftherios;Mathew, Jinu S.;McMillan, Lynne;Pearce, John E.;Rawlinson, Fiona L.;Sherlock, Alexandra E.;Walton, Robert [Organic Process Research and Development,2012,vol. 16,# 12,p. 1897 - 1904]
697739-03-0
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$8.00/250mg
4637-24-5
611 suppliers
$5.00/25g
1082040-43-4
212 suppliers
$26.00/100mg
850462-64-5
97 suppliers
$11.00/250mg
1082040-43-4
212 suppliers
$26.00/100mg
175278-29-2
124 suppliers
$9.00/1g
1082040-43-4
212 suppliers
$26.00/100mg