6-BROMONICOTINAMIDE synthesis
- Product Name:6-BROMONICOTINAMIDE
- CAS Number:889676-37-3
- Molecular formula:C6H5BrN2O
- Molecular Weight:201.02
139585-70-9
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$10.00/1g
889676-37-3
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$29.00/250mg
Yield:889676-37-3 92%
Reaction Conditions:
with sodium t-butanolate in 5,5-dimethyl-1,3-cyclohexadiene;ethanol; for 4 h;Reflux;
Steps:
3 Example 3
A mixture of 2-bromo-5-cyanopyridine (10 mmol, 1.83 g),Sodium tert-butoxide (0 · 1 mmol, 9 · 6 mg)(V: V = 3: 1) in a mixed solvent of xylene / ethanol (V: V = 3: 1). After the reaction was allowed to proceed for 4 hours, the reaction was stopped,After drying, the residue was purified by silica gel column chromatography to give 1.84 g of 2-bromo-5-amidopyridine as a white solid
References:
CN104016913,2016,B Location in patent:Paragraph 0033-0036
6311-35-9
374 suppliers
$15.00/1g
889676-37-3
93 suppliers
$29.00/250mg