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ChemicalBook CAS DataBase List 2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI)
57224-14-3

2H-Pyrrole-5-carboxylic acid, 3,4-dihydro-, methyl ester (9CI) synthesis

4synthesis methods
2133-40-6 Synthesis
Methyl L-prolinate hydrochloride

2133-40-6
436 suppliers
$8.00/5g

-

Yield:57224-14-3 88 %

Reaction Conditions:

Stage #1: L-proline methyl ester monohydrochloridewith triethylamine in dichloromethane at 0;
Stage #2: with N-chloro-succinimide in dichloromethane at 0 - 20;

References:

Mansour, Ali;Gagosz, Fabien [Organic Letters,2022,vol. 24,# 39,p. 7200 - 7204] Location in patent:supporting information