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ChemicalBook CAS DataBase List 5-PHENYL-1,3,4-OXADIAZOLE-2-CARBONYL CHLORIDE
98591-60-7

5-PHENYL-1,3,4-OXADIAZOLE-2-CARBONYL CHLORIDE synthesis

5synthesis methods
-

Yield:-

Reaction Conditions:

with thionyl chloride for 4 h;Reflux;

Steps:

4.3 5-Phenyl-1,3,4-oxadiazole-2-carbonyl chloride (5)

5-Phenyl-1,3,4-oxadiazole-2-carboxylic acid (4) (400 mg, 2.11 mmol) was dissolved in thionyl chloride (4mL) and refluxed for four hours. Then the mixture was concentrated in vacuum and used without any purification.

References:

Polyak, Maria;Varga, Gergely;Szilagyi, Bence;Juhasz, Laszlo;Docsa, Tibor;Gergely, Pal;Begum, Jaida;Hayes, Joseph M.;Somsak, Laszlo [Bioorganic and Medicinal Chemistry,2013,vol. 21,# 18,p. 5738 - 5747]

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