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ChemicalBook CAS DataBase List 5-BROMO-2-(1-METHYL-1H-TETRAZOL-5-YL)-PYRIDINE
380380-63-2

5-BROMO-2-(1-METHYL-1H-TETRAZOL-5-YL)-PYRIDINE synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium cyanide / N,N-dimethyl-formamide / 7 h / 150 °C / Inert atmosphere
2: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 3 h / 110 °C / Inert atmosphere
3: sodium hydroxide / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

References:

Im, Weon Bin;Choi, Sun Ho;Park, Ju-Young;Choi, Sung Hak;Finn, John;Yoon, Sung-Hwa [European Journal of Medicinal Chemistry,2011,vol. 46,# 4,p. 1027 - 1039]

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