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ChemicalBook CAS DataBase List 5-Amino-3-(4-chlorophenyl)-1,2,4-thiadiazole
19922-07-7

5-Amino-3-(4-chlorophenyl)-1,2,4-thiadiazole synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium tert-butylate / dimethyl sulfoxide / 4 h / 25 °C / Sealed tube; Schlenk technique
2: iodine / dimethyl sulfoxide; water / 10 h / 25 °C / Sealed tube; Schlenk technique; Green chemistry

References:

Chai, Ling;Lai, Zhenzhen;Xia, Qiangqiang;Yuan, Jiangpei;Bian, Qilong;Yu, Mingjian;Zhang, Wenkai;Xu, Yuanqing;Xu, Hao [European Journal of Organic Chemistry,2018,vol. 2018,# 31,p. 4338 - 4344]

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