ChemicalBook CAS DataBase List 2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE

2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE synthesis

5synthesis methods

Product Name:2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE
CAS Number:443955-90-6
Molecular formula:C8H7NO3
Molecular Weight:165.15

(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanol

443955-89-3
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2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE

443955-90-6
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$68.00/25mg

Yield:443955-90-6 61%

Reaction Conditions:

with manganese(IV) oxide in dichloromethane; for 72 h;

Steps:

4.c

c) 2,3-Dihydro-[1 ,4]dioxino[2,3-c]pyridine-7-carboxaldehyde; A solution of (2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)-methanol (250 mg, 1.5 mmol) in dichloromethane (5 mL) was treated with manganese dioxide (650 mg, 7.5 mmol). After 3 days the mixture was filtered and evaporated affording a white solid (150 mg, 61 %); MS (APCI+) m/z 166 (MH+).

References:

WO2006/81264,2006,A1 Location in patent:Page/Page column 26-27

501-30-4 Synthesis