成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

    • Welcome to chemicalbook!
    Chinese English Japanese Germany Korea
    400-158-6606
    Try our best to find the right business for you.
    Do not miss inquiry messages Please log in to view all inquiry messages.

    Welcome back!

    ChemicalBook CAS DataBase List 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBALDEHYDE
    438577-61-8

    4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBALDEHYDE synthesis

    3synthesis methods
    317318-96-0 Synthesis
    (4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL)METHANOL

    317318-96-0
    67 suppliers
    $65.00/50mg

    -

    Yield:438577-61-8 82%

    Reaction Conditions:

    with Dess-Martin periodane in dichloromethane at 20; for 3 h;Dess-Martin Oxidation;

    Steps:

    2.3 Synthesis of 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde (5):

    To a solution of the (4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methanol (4) (4.57 mmol) in dichloromethane (200 mL) was added Dess-Martin periodinane(9.15 mmol). The reaction mixture was stirred at RT for 3 h, after which time it was quenched with 20% aq Na2S2O3 (20 mL) and sat.aq NaHCO3 (80 mL). The mixture was stirred until the aq layer was clear. The aq layer was extracted with DCM (3 x 50 mL). The combined organics layers were dried over Na2SO4and evaporated under reduced pressure. The residue was purified by column chromatography over silica to obtain the desired compound 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde (5) (yield 82%).

    References:

    Kesari, Chekrapani;Rama, Koteshwar Rao;Sedighi, Khwajanezrabodin;Stenvang, Jan;Bj?rkling, Fredrik;Kankala, Shravankumar;Thota, Niranjan [Synthetic Communications,2021,vol. 51,# 9,p. 1406 - 1416] Location in patent:supporting information