ChemicalBook CAS DataBase List 4-CHLOROPHENYL SULFOXIDE

4-CHLOROPHENYL SULFOXIDE synthesis

11synthesis methods

Product Name:4-CHLOROPHENYL SULFOXIDE
CAS Number:3085-42-5
Molecular formula:C12H8Cl2OS
Molecular Weight:271.16

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Benzenesulfinothioic acid, 4-chloro-, 4-chlorophenyl ester

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Yield: 89 %Chromat. ， 11 %Chromat.

Reaction Conditions:

with aluminum (III) chloride;thionyl chloride at 25;

Steps:

Approach 2
General procedure: The reactions were conducted in the fume hood at 25 °C, with the molar ratio of PhX:SOCl₂:AlCl₃being 2:1:1 and usage of SOCl₂approximately 10 mmol. For each reaction, SOCl₂ was added dropwise to the PhX-AlCl₃mixture (X=CH3 or Cl) with constantstirring. The reaction took place quickly, indicated by bubbling asabove. After all the SOCl₂ was added, the reaction went to completion, indicated by cessation of bubbling. Then aqueous work-up wasperformed as above. The final product was characterised by GC-MS, and the results are shown in Table 1.

References:

Sun, Xiaoping;Haas, David;McWilliams, Samantha;Smith, Benjamin;Leaptrot, Katrina [Journal of Chemical Research,2013,vol. 37,# 12,p. 736 - 744]

108-90-7
651 suppliers
$10.00/25G

3085-42-5
113 suppliers
$10.00/1g

References