ChemicalBook CAS DataBase List 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE synthesis

6synthesis methods

Product Name:4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
CAS Number:4362-40-7
Molecular formula:C6H11ClO2
Molecular Weight:150.6

96-24-2
300 suppliers
$11.00/5g

4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

4362-40-7
88 suppliers
$55.00/5g

Yield: 89%

Reaction Conditions:

with toluene-4-sulfonic acid in acetone

Steps:

1 EXAMPLE 1
EXAMPLE 1 p-Toluenesulfonic acid (1.79 g) was added to a mixture of 3-chloro-1,2-propanediol (104.49 g, 0.945 mol) and acetone (1500 ml) and the resulting mixture was stirred for 12 hours at 25° C. After completion of the reaction, acetone was removed in vacuo and the crude product was distilled to give 128.01 g of 4-chloromethyl-2,2-dimethyl-1,3-dioxolane (yield 89%, b.p. 45° C. at 5 mmHg).

References:

Daiso Co., Ltd. US6143908, 2000, A