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50677-27-5

4-CHLORO-N'-(2-CHLOROACETYL)BENZENECARBOHYDRAZIDE synthesis

4synthesis methods
-

Yield:50677-27-5 88%

Reaction Conditions:

Stage #1: chloroacetic acidwith 2,6-dimethylpyridine;O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate in dichloromethane at 25; for 0.166667 h;
Stage #2: 4-chlorobenzoic acid hydrazide at 20; for 3 h;

References:

Gurupadaswamy, Handuvinahalli Devanna;Girish, Virupaksha;Zameer, Farhan;Hegdekatte, Raghavendra;Chauhan, Jyoti Bala;Khanum, Shaukath Ara [Archiv der Pharmazie,2013,vol. 346,# 11,p. 805 - 811]