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ChemicalBook CAS DataBase List 4-CHLORO-5-NITRO-2-TOLUIDINE
34648-99-2

4-CHLORO-5-NITRO-2-TOLUIDINE synthesis

5synthesis methods
-

Yield:34648-99-2 92%

Reaction Conditions:

Stage #1: 4-chloro-2-methylbenzeneaminewith tert-butyl methyl ether;nitric acid in tetrahydrofuran at 0;
Stage #2: with sulfuric acid in dichloromethane at 0; for 1 h;Further stages.;

References:

Zhang, Pingsheng;Cedilote, Miall;Cleary, Thomas P.;Pierce, Michael E. [Tetrahedron Letters,2007,vol. 48,# 49,p. 8659 - 8664]

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