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ChemicalBook CAS DataBase List (4-BROMO-PHENYL)-PIPERIDIN-1-YL-METHANONE
98612-93-2

(4-BROMO-PHENYL)-PIPERIDIN-1-YL-METHANONE synthesis

13synthesis methods
-

Yield:98612-93-2 98 %

Reaction Conditions:

Stage #1: 4-Bromobenzoic acidwith oxalyl dichloride;N,N-dimethyl-formamide in dichloromethane at 20;Inert atmosphere;
Stage #2: piperidinewith triethylamine in dichloromethane at 20;Inert atmosphere;

References:

Veatch, Alexander M.;Liu, Shubin;Alexanian, Erik J. [Angewandte Chemie - International Edition,2022,vol. 61,# 50,art. no. E202210772][Angew. Chem.,2022,vol. 134,# 50] Location in patent:supporting information

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