ChemicalBook CAS DataBase List 4-BIPHENYLSULFONYL CHLORIDE

4-BIPHENYLSULFONYL CHLORIDE synthesis

4synthesis methods

Product Name:4-BIPHENYLSULFONYL CHLORIDE
CAS Number:1623-93-4
Molecular formula:C12H9ClO2S
Molecular Weight:252.72

92-52-4 Synthesis

92-52-4
397 suppliers
$9.00/5g

1623-93-4
175 suppliers
$5.00/5mg

Yield:-

Reaction Conditions:

with chlorosulfonic acid in chloroform at 20; for 0.75 h;

Steps:

Syntheses of substituted benzenesulfonyl chlorides
General procedure: The chemical synthesis was started with chlorosulfonylationof the substituted benzenes (S1) individually in dry chloroformby dropwise addition of chlorosulfonic acid over a period of45-60 mins at 0-5 C. After completion of chlorosulfonic acid addition,the reaction mixture was stirred for additional 45 min atroom temperature and the mixture was poured over crushed ice.The mixture was extracted thrice with 50 ml chloroform whichwas dried overnight in presence of anhydrous sodium sulfate. Afterevaporation of the solvent chloroform, substituted benzenesulfonylchlorides (I1) were obtained individually in solid formswhich were used for next step without any purification.

References:

Adhikari, Nilanjan;Halder, Amit K.;Mallick, Sumana;Saha, Achintya;Saha, Kishna D.;Jha, Tarun [Bioorganic and Medicinal Chemistry,2016,vol. 24,# 18,p. 4291 - 4309]

FullText