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ChemicalBook CAS DataBase List 4-Amino-3-hydroxybenzoic acid
2374-03-0

4-Amino-3-hydroxybenzoic acid synthesis

3synthesis methods
-

Yield:-

Reaction Conditions:

with palladium on activated charcoal;hydrogen in methanol at 20;

Steps:

4 Preparation of 4-amino-3-hydroxybenzoic acid (Compound 4B)

Compound 4A (85 mg, 0.8 mmol) was dissolved in methanol.After adding the Pd/C catalyst, the reaction was allowed to proceed overnight at room temperature under hydrogen atmosphere, and the reaction was completed.Filtration removes solid insolubles,After several layers were concentrated under reduced pressure, the obtained solid was used in the next step without further purification.

References:

CN104045552,2019,B Location in patent:Paragraph 0114; 0115; 0118; 0119

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