4-Acetamidosalicylic acid synthesis
- Product Name:4-Acetamidosalicylic acid
- CAS Number:50-86-2
- Molecular formula:C9H9NO4
- Molecular Weight:195.17
65-49-6
494 suppliers
$6.00/25g
50-86-2
117 suppliers
$75.00/500 mg
Yield: 92%
Reaction Conditions:
with acetic anhydride in ethanol
Steps:
11 4-acetamidosalicylic acid
EXAMPLE 11 4-acetamidosalicylic acid 30.6 grs (0.2 mol) p-aminosalicylic acid and 100 cc ethanol were introduced into a 250 ml flask, and the mixture was heated to 40° C. 20.4 grs (0.2 mol) acetic anhydride was then added at such a rate that the temperature did not exceed 50° C. When the addition was complete, the mixture was stirred at 50° C. for 3 hours. The product was filtered. Weight: 36 grs m.p. = 235° C. Yield = 92%.
References:
Anphar, S.A. US4138492, 1979, A
108-24-7
5 suppliers
$14.00/250ML
65-49-6
494 suppliers
$6.00/25g
50-86-2
117 suppliers
$75.00/500 mg
556-08-1
353 suppliers
$6.00/10g
50-86-2
117 suppliers
$75.00/500 mg
65-49-6
494 suppliers
$6.00/25g
75-36-5
583 suppliers
$17.92/100G
50-86-2
117 suppliers
$75.00/500 mg
108-24-7
5 suppliers
$14.00/250ML
133-10-8
134 suppliers
$57.00/100g
50-86-2
117 suppliers
$75.00/500 mg