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ChemicalBook CAS DataBase List 4,5,6-TRICHLORONICOTINIC ACID ETHYL ESTER
181261-73-4

4,5,6-TRICHLORONICOTINIC ACID ETHYL ESTER synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: NCS / dimethylformamide / 72 h / 20 °C
2: 6.04 g / POCl3; TEA / 4 h / 60 °C

References:

Wallace, Eli M.;Lyssikatos, Joseph;Blake, James F.;Seo, Jeongbeob;Yang, Hong Woon;Yeh, Tammie C.;Perrier, Michele;Jarski, Heidi;Marsh, Vivienne;Poch, Gregory;Livingston, Michelle Goyette;Otten, Jennifer;Hingorani, Gary;Woessner, Rich;Lee, Patrice;Winkler, James;Koch, Kevin [Journal of Medicinal Chemistry,2006,vol. 49,# 2,p. 441 - 444]

846541-71-7 Synthesis
5-Chloro-4,6-dihydroxynicotinic acid ethyl ester

846541-71-7
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4,5,6-TRICHLORONICOTINIC ACID ETHYL ESTER

181261-73-4
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