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ChemicalBook CAS DataBase List 4,4,5,5,6,6,6-HEPTAFLUORO-1-PHENYL-1,3-HEXANEDIONE
53580-21-5

4,4,5,5,6,6,6-HEPTAFLUORO-1-PHENYL-1,3-HEXANEDIONE synthesis

2synthesis methods
-

Yield: 80%

Reaction Conditions:

Stage #1:ethyl heptafluorobutyrate with sodium methylate in methanol;diethyl ether at 0; for 0.5 h;
Stage #2:acetophenone in methanol;diethyl ether at 20; for 16 h;Further stages.;Claisen condensation;

References:

Büttner, Stefan;Lubbe, Mathias;Reinke, Helmut;Fischer, Christine;Langer, Peter [Tetrahedron,2008,vol. 64,# 34,p. 7968 - 7976]

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