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ChemicalBook CAS DataBase List 4-(3,4-DICHLOROPHENYL)BUT-3-EN-2-ONE
74546-02-4

4-(3,4-DICHLOROPHENYL)BUT-3-EN-2-ONE synthesis

2synthesis methods
-

Yield:74546-02-4 100%

Reaction Conditions:

with sodium hydroxide in water at 20; for 2 h;

Steps:

9.1 Stepl

Stepl: To a solution of 1 (3.5 g, 20 mmol) in acetone (20 mL) and ethanol (2 mL) was added aqueous NaOH (10%, 15 mL) and water (80 mL). The mixture was stirred at rt for 2 h, extracted with EA (3 x 50 mL). The organic layers were dried and concentrated to give 2 (4.3 g, 100%).

References:

WO2013/29057,2013,A2 Location in patent:Paragraph 0433