3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER synthesis
- Product Name:3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
- CAS Number:315717-77-2
- Molecular formula:C13H18N2O2
- Molecular Weight:234.29
604798-64-3
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315717-77-2
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$137.50/0.5g
604798-67-6
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Yield:604798-67-6 26% ，315717-77-2 15%
Reaction Conditions:
Stage #1: (3R,4S)-3-azidomethyl-1-benzyloxycarbonyl-4-hydroxypyrrolidinewith diethylamino-sulfur trifluoride in dichloromethane at 20;
Stage #2: with platinum(IV) oxide;hydrogen in ethanol at 20; under 760.051 Torr; for 4.5 h;
References:
Asahina, Yoshikazu;Takei, Masaya;Kimura, Tetsuya;Fukuda, Yasumichi [Journal of Medicinal Chemistry,2008,vol. 51,# 11,p. 3238 - 3249] Location in patent:experimental part
124-63-0
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$10.00/5g
315718-05-9
106 suppliers
$60.00/100mg
315717-77-2
36 suppliers
$137.50/0.5g