ChemicalBook CAS DataBase List 3-CHLOROPROPYL PHENYL SULFIDE

3-CHLOROPROPYL PHENYL SULFIDE synthesis

11synthesis methods

Product Name:3-CHLOROPROPYL PHENYL SULFIDE
CAS Number:4911-65-3
Molecular formula:C9H11ClS
Molecular Weight:186.7

108-98-5
4 suppliers
$26.30/10g

109-70-6 Synthesis

109-70-6
486 suppliers
$10.00/5g

4911-65-3
29 suppliers
$73.90/5g

Yield:4911-65-3 100%

Reaction Conditions:

with triethylamine in tetrahydrofuran at 25; for 12 h;

Steps:

R Procedure R

Procedure R [(3-CHLOROPROPYL)SULFANYL]BENZENE: A mixture of benzenethiol (0.550 9, 5.00 mmol), 1-bromo-3-chloropropane (106 mg, 5.50 mmol), TEA (1.01 g, 10.0 mmol) and THF (10.0 ML) was stirred for 12 h at 25° C. The resulting crude mixture was diluted with water (40 ML), the aqueous layer was extracted with CH2Cl2 (3*30 ML).. The combined organic layers were concentrated in vacuo and the residue was purified by preparative TLC using hexane:EtOAc (10:1) to give the desired product [(3-chloropropyl)sulfanyl]benzene (1.05 g, 100%)..

References:

US6727264,2004,B1 Location in patent:Page column 138; 139

24536-40-1 Synthesis