3-BROMO-3'-FLUOROBENZOPHENONE synthesis
- Product Name:3-BROMO-3'-FLUOROBENZOPHENONE
- CAS Number:75762-58-2
- Molecular formula:C13H8BrFO
- Molecular Weight:279.1
226260-01-1
79 suppliers
$15.00/1g
108-36-1
460 suppliers
$10.00/1g
75762-58-2
16 suppliers
$75.00/250mg
Yield:75762-58-2 30%
Reaction Conditions:
Stage #1: 1,3-dibromobenzenewith iodine;magnesium in diethyl ether at 20 - 30;Inert atmosphere;
Stage #2: 3-fluoro-N-methoxy-N-methylbenzamide in diethyl ether at 0 - 20;Inert atmosphere;
References:
Kishore Kumar;Chavarria, Gustavo E.;Charlton-Sevcik, Amanda K.;Arispe, Wara M.;MacDonough, Matthew T.;Strecker, Tracy E.;Chen, Shen-En;Siim, Bronwyn G.;Chaplin, David J.;Trawick, Mary Lynn;Pinney, Kevin G. [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 4,p. 1415 - 1419] Location in patent:supporting information; experimental part