3-AMINO-6-PHENYLPYRIDAZINE synthesis
- Product Name:3-AMINO-6-PHENYLPYRIDAZINE
- CAS Number:14966-91-7
- Molecular formula:C10H9N3
- Molecular Weight:171.2
5469-69-2
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$6.00/10g
98-80-6
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$5.00/5g
14966-91-7
65 suppliers
$52.00/100 mg
Yield: 79%
Reaction Conditions:
with tetrakis(triphenylphosphine) palladium(0);potassium carbonate in 1,4-dioxane;water;toluene for 12 h;Reflux;
Steps:
11-3; 6
General procedure: phenylboronic acid (8.9 g, 0.073 mol), 4-bromo-2-naphthylamine (13.5 g, 0.061 mol), tetrakis(triphenylphosphine)palladium (3.62 g, 0.003 mol), potassium carbonate (25.3) g, 0.183 mol) was added to 75 mL of 1,4-dioxane, 75 mL of toluene, and 30 mL of distilled water, and refluxed for 12 hours.After cooling to room temperature, extraction with ethyl acetate, and separation by column chromatography to give [Intermediate 1-c] 10 g (75% yield).
References:
SFC Ltd.;Cha Sun-uk;Jeong Gyeong-seok;Park Seok-bae;Kim Hui-dae;Lee Yu-rim;Song Ju-man;Hwang Mun-chan KR102193832, 2020, B1 Location in patent:Paragraph 0198; 0207-0210; 0320-0324
88497-27-2
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$41.71/1gm:
98-80-6
740 suppliers
$5.00/5g
14966-91-7
65 suppliers
$52.00/100 mg
38956-80-8
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$35.00/200 μmol
14966-91-7
65 suppliers
$52.00/100 mg
20375-65-9
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$15.00/250mg
14966-91-7
65 suppliers
$52.00/100 mg
187973-60-0
101 suppliers
$9.00/100mg
98-80-6
740 suppliers
$5.00/5g
14966-91-7
65 suppliers
$52.00/100 mg