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354813-00-6

3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: aq. NaOH / methanol
2: SOCl2
3: NH3 / acetonitrile

References:

Baxter, Andrew;Brough, Steve;Cooper, Anne;Floettmann, Eike;Foster, Steve;Harding, Christine;Kettle, Jason;McInally, Tom;Martin, Craig;Mobbs, Michelle;Needham, Maurice;Newham, Pete;Paine, Stuart;St-Gallay, Steve;Salter, Sylvia;Unitt, John;Xue, Yafeng [Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,# 11,p. 2817 - 2822]