3,5-DIMETHYLTHIOANISOLE synthesis
- Product Name:3,5-DIMETHYLTHIOANISOLE
- CAS Number:66794-11-4
- Molecular formula:C9H12S
- Molecular Weight:152.26
38360-81-5
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74-88-4
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$15.00/10g
66794-11-4
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$60.00/100mg
Yield:66794-11-4 88%
Reaction Conditions:
with potassium carbonate;tetrabutylammomium bromide in dimethyl sulfoxide at 20; for 16 h;
Steps:
2.a
2.a 1,3-Dimethyl-5-methylsulfanyl-benzene10.0 g (0.072 mol) of 3,5-dimethylbenzenethiol, 9.95 g (0.072 mol) of potassium carbonate and 0.46 g (1.4 mmol) of tetrabutylammonium bromide are suspended in 20 ml of dimethylsulfoxide under argon. Iodomethane (10.2 g, 0.072 mol) is added dropwise, and the mixture is stirred 16 h at ambient temperature. After pouring the mixture into water, the product is extracted with ether, washed with water, dried over sodium sulfate and concentrated in vacuo. The crude product 9.6 g (0.063 mol; 88%) is obtained as a slightly yellow oil, and is used for the next step without further purification. Elemental analysis C9H12S (152.26) C [%] H [%] S [%] calculated: 71.00 7.94 21.06 found: 70.82 8.01 20.91
References:
US6949678,2005,B2 Location in patent:Page/Page column 57
22445-41-6
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67-68-5
1235 suppliers
$15.00/100g
66794-11-4
29 suppliers
$60.00/100mg
556-96-7
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$6.00/5g
67-68-5
1235 suppliers
$15.00/100g
66794-11-4
29 suppliers
$60.00/100mg
5271-38-5
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$27.89/5g
22445-41-6
206 suppliers
$5.00/5g
66794-11-4
29 suppliers
$60.00/100mg
624-92-0
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$26.39/5ml
556-96-7
373 suppliers
$6.00/5g
66794-11-4
29 suppliers
$60.00/100mg