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ChemicalBook CAS DataBase List 3,5-DIISOPROPYLSALICYLIC ACID
2215-21-6

3,5-DIISOPROPYLSALICYLIC ACID synthesis

2synthesis methods
-

Yield:2215-21-6 40%

Reaction Conditions:

sulfuric acid in isopropyl alcohol

Steps:

7 2-Hydroxy-3,5-diisopropylbenzoic hydrazide sulphate
EXAMPLE 7 2-Hydroxy-3,5-diisopropylbenzoic hydrazide sulphate Salicylic acid (0.67 m) was alkylated with 1.33 m isopropanol using 3.3 m concentrated sulphuric acid as catalyst at 70°C for six hours, to give 2-hydroxy-3,5-diisopropyl benzoic acid (m.p. 113°-116°C) in 40% yield.

References:

Ciba-Geigy Corporation US3932505, 1976, A

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