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142505-28-0

3-(4-TERT-BUTYLPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: 4-t-butylphenylacetic acidwith lithium diisopropyl amide in tetrahydrofuran at -20 - 20; for 4 h;
Stage #2: ethyl trifluoroacetate, in tetrahydrofuran at -65; for 0.25 h;

References:

Jiang, Jun;Lu, Wenxin;Lv, Hui;Zhang, Xumu [Organic Letters,2015,vol. 17,# 5,p. 1154 - 1156] Location in patent:supporting information

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