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85606-96-8

3-(4-FLUORO-PHENYL)-PIPERAZIN-2-ONE synthesis

1synthesis methods
-

Yield:-

Steps:

13 3-(4-fluorophenyl)-piperazin-2-one

EXAMPLE 13 3-(4-fluorophenyl)-piperazin-2-one 24 g (0.125 mol) of 3-(4-fluorophenyl)-5,6-dihydro-2(1H)-pyrazinone are hydrogenated and worked up as described in Example 1, and the product is recrystallized from ethyl acetate. Yield: 15 g=61.8% of theory (molecular weight 194), Melting point: 105°-108° C.

References:

US4598079,1986,A

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