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3,4-DICHLOROPHENETHYLAMINE synthesis
- Product Name:3,4-DICHLOROPHENETHYLAMINE
- CAS Number:21581-45-3
- Molecular formula:C8H9Cl2N
- Molecular Weight:190.07
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3218-49-3
261 suppliers
$5.00/5g
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21581-45-3
104 suppliers
$19.00/1g
Yield:21581-45-3 92%
Reaction Conditions:
with ammonia;hydrogen;nickel in ethanol;water; under 760.051 Torr; for 6 h;
Steps:
A
Method A. A solution of 3,4-dichlorophenylacetonitrile (3.001 g, 16.13 mmol) in ethanol (33 mL) and 29% NH4OH (6.7 ml, 611.2 mg, 17.44 mmol) in the presence of Raney Ni (333 mg, 3.887 mmol) was stirred vigorously under H2 (1 atm) for 6 h. The reaction mixture was filtered through Celite then the filtrate was concentrated under reduced pressure to give 2-(3,4-dichlorophenyl)ethylamine (2.82 g, 92%) as a pale yellow oil. LC/MS ((10%-99% CH3CN (0.035% TFA)/H2O (0.05% TFA)), m/z: M+1 obs=190.3; tr=0.80 min.
References:
US2009/124655,2009,A1 Location in patent:Page/Page column 27-28
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37630-23-2
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21581-45-3
104 suppliers
$19.00/1g
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52123-62-3
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21581-45-3
104 suppliers
$19.00/1g
![Carbamic acid, [2-(3,4-dichlorophenyl)ethyl]-, phenyl ester (9CI)](/CAS/20210305/GIF/792909-20-7.gif)
792909-20-7
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21581-45-3
104 suppliers
$19.00/1g
![Carbamic acid, N-[2-(3,4-dichlorophenyl)ethyl]-, 1,1-dimethylethyl ester](/CAS/20210305/GIF/426826-80-4.gif)
426826-80-4
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21581-45-3
104 suppliers
$19.00/1g