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ChemicalBook CAS DataBase List 3-(4-BROMOPHENOXY)PROPANOIC ACID
93670-18-9

3-(4-BROMOPHENOXY)PROPANOIC ACID synthesis

7synthesis methods
-

Yield:93670-18-9 98%

Reaction Conditions:

with N-Bromosuccinimide;sodium hydroxide in water at 20; for 1 h;

Steps:

8

Keep at room temperature, compound III (152 g, 0.9 mole) and sodium hydroxide (80 g, 2 mole) in 1.5 liters of solution added in batches in NBS (178 g, 1 mole). After dropping stirring 1 hour. For concentrated hydrochloric acid to adjust the pH to 2 - 3. Collecting the solid and dry it. The product 218 g (98%).

References:

CN106699716,2017,A Location in patent:Paragraph 0020; 0033

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