3,4,5-TRIFLUOROBENZOTRIFLUORIDE synthesis
- Product Name:3,4,5-TRIFLUOROBENZOTRIFLUORIDE
- CAS Number:80172-04-9
- Molecular formula:C7H2F6
- Molecular Weight:200.08
50594-82-6
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$6.00/5g
80172-04-9
95 suppliers
$29.00/1g
Yield: 75%
Reaction Conditions:
with potassium fluoride;nitrobenzene;1,3-dimethyl-2-(N',N',N",N"-tetramethylguanidino)-4,5-dihydro-3H-imidazolium chloride in sulfolane at 200 - 220; under 6750.68 Torr; for 17 h;
Steps:
3
Example 3; Preparation method of 3,4,5-trifluorobenzotrifluoride; 860 g of dry sulpholane and 524 g of dry KF were initially charged with exclusion of moisture in an autoclave, and 500 g of 3,4,5-trichlorobenzotrifluoride, 5 g of nitrobenzene and 25 g of CNC catalyst were added. The vessel was sealed and the mixture subsequently heated to 200° C. for 5 h and then to 220° C. for a further 12 h. During the reaction, a maximum total pressure of 9 bar arose. The mixture was then cooled to 20° C. and decompressed into a cooled receiver. The product was distilled off at standard pressure. After redistillation of the crude product, 300 g of 3,4,5-trifluorobenzotrifluoride (75% of theory) were obtained as a colourless liquid.
References:
Pleschke, Axel;Marhold, Albrecht US2006/9643, 2006, A1 Location in patent:Page/Page column 5
2923-18-4
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143418-49-9
398 suppliers
$5.00/1g
80172-04-9
95 suppliers
$29.00/1g