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ChemicalBook CAS DataBase List 3,4,5-Trifluorobenzenemethanol
220227-37-2

3,4,5-Trifluorobenzenemethanol synthesis

1synthesis methods
138526-69-9 Synthesis
5-Bromo-1,2,3-trifluorobenzene

138526-69-9
412 suppliers
$6.00/5g

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Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: magnesium / tetrahydrofuran / 1 h / 40 °C / Inert atmosphere
1.2: 1 h / 20 °C / Inert atmosphere; Cooling with ice
2.1: sodium tetrahydroborate / water; ethanol / 2 h / 20 °C / Cooling with ice

References:

DIC CORPORATION;Tojo, Kenta;Takeuchi, Kiyofumi;Osawa, Masashi;Kaneoya, Masakazu;Kusumoto, Tetsuo US2014/275577, 2014, A1

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