1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE synthesis
- Product Name:1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE
- CAS Number:288252-38-0
- Molecular formula:C11H8Cl2N2O
- Molecular Weight:255.1
187998-35-2
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288252-38-0
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$631.85/250MG
Yield:288252-38-0 100%
Reaction Conditions:
with thionyl chloride for 1 h;Reflux;
Steps:
9
A solution of l-(4-chloro-phenyl)-5-methyl-lH-pyrazole-4-carboxylic acid (1.5 g, 6.3 mmol) in thionyl chloride (18 rnL) is warmed to reflux for 1 hour. After cooling to room temperature, the reaction mixture is concentrated in vacuo to afford l-(4-chloro-phenyl)- 5-methyl-lH-pyrazole-4-carbonyl chloride as a tan solid (1.6 g, 100 %) which is used without further purification.
References:
WO2009/137338,2009,A1 Location in patent:Page/Page column 61
169548-94-1
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288252-38-0
18 suppliers
$631.85/250MG