1-ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carbonitrile synthesis

1synthesis methods

Product Name:1-ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carbonitrile
CAS Number:28657-79-6
Molecular formula:C12H9N3O3
Molecular Weight:243.2182

28657-80-9 Synthesis

Yield:28657-79-6 21%

Reaction Conditions:

Stage #1: cinoxacinwith polyphosphate ester;ammonia in chloroform at 119 - 123; for 24 h;
Stage #2: with polyphosphate ester at 120; for 1 h;

References:

Korthals, Keith A.;Delia, Thomas J. [Organic Preparations and Procedures International,2004,vol. 36,# 6,p. 597 - 600]

1-ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carbonitrile Related Search:

CINNOLINE