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ChemicalBook CAS DataBase List Carbamic acid, (2,6-dioxo-3-piperidinyl)-, phenylmethyl ester (9CI)
24666-55-5

Carbamic acid, (2,6-dioxo-3-piperidinyl)-, phenylmethyl ester (9CI) synthesis

5synthesis methods
-

Yield: 92%

Reaction Conditions:

with urea in dimethyl sulfoxide at 150; for 2 h;Solvent;Temperature;

Steps:

3.4
N-CBZ-L-glutamic acid 2.81 g (0.01 mol),Urea 1.2g (0.2mol) was added to DMSO to dissolve and reflux at 150 ° C. After 2 h, the temperature was lowered.HCl gas, a white solid 1.518 g, a yield of 92%;

References:

Wang Yanping;Yang Yi;Zhang Xiaoling;Zhou Qinghe;Xu Congying CN108218833, 2018, A Location in patent:Paragraph 0043; 0044; 0057; 0058; 0063; 0071; 0072

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