2-PHENYLIMIDAZO[1,2-A]PYRIMIDINE synthesis
- Product Name:2-PHENYLIMIDAZO[1,2-A]PYRIMIDINE
- CAS Number:15764-47-3
- Molecular formula:C12H9N3
- Molecular Weight:195.22
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Yield:15764-47-3 90%
Reaction Conditions:
in propan-2-one; for 5 h;Reflux;
Steps:
13 Preparation of compound LA93:
10.0g (0.105mol) of 2-aminopyrimidine and 21.0g (0.105mol) of 2-bromo-1-phenylethanone were mixed, 150mL of acetone was added, and the reaction was stirred at reflux at elevated temperature for 5 hours, cooled to room temperature, filtered, and filtered The cake was washed with acetone, and the obtained solid was dissolved in 200 mL of 3N dilute hydrochloric acid. The temperature was heated and refluxed and stirred for 1 hour. 15% dilute ammonia was added dropwise to adjust to pH-8, cooled to room temperature, filtered, and the filter cake was recrystallized with ethanol to obtain Compound LA93, white solid, yield 90%.
References:
CN113201027,2021,A Location in patent:Paragraph 0159-0163
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$45.00/10mg
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$6.00/10g
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15764-47-3
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