2-Methyl-2-hydroxypropionamide synthesis
- Product Name:2-Methyl-2-hydroxypropionamide
- CAS Number:13027-88-8
- Molecular formula:C4H9NO2
- Molecular Weight:103.12
Yield:-
Reaction Conditions:
with sulfuric acid in waterIndustry scale;
Steps:
The first stage of producing either MAA or methacrylate esters from ACH involves hydrolysis of the ACH in a hydrolysis system; the general chemistry of the hydrolysis process for both MAA and methacrylate esters may be very similar. Shown at 12 and 32 in FIG. 1 is hydrolysis of the ACH in a hydrolysis system to produce a hydrolysis mixture that contains α-sulfatoisobutyramide (“SIBAM”) and α-hydroxyisobutyramide (“HIBAM”). ACH and an excess of sulfuric acid are fed into hydrolysis reactor 12. It is preferable to use ACH that has low levels of water and other impurities in the hydrolysis step. The sulfuric acid serves as both a specific reactant and a solvent for the reaction. Using sulfuric acid at concentrations of greater than 95% is also preferred. In an alternative embodiment, oleum or a combination of sulfuric acid and oleum may be used in place of sulfuric acid. Either hydrolysis system may contain a single reactor or multiple reactors connected in series and may also employ one or more reactant addition points.
References:
Carlson JR., Curtis Ingstad;DeCourcy, Michael Stanley;Juliette, Jamie Jerrick John US2003/208093, 2003, A1 Location in patent:Page/Page column 3; Sheet 1
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