ChemicalBook CAS DataBase List 2-Bromobiphenyl

2-Bromobiphenyl synthesis

12synthesis methods

Product Name:2-Bromobiphenyl
CAS Number:2052-07-5
Molecular formula:C12H9Br
Molecular Weight:233.1

583-53-9
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$10.00/5g

98-80-6 Synthesis

98-80-6
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$5.00/5g

2052-07-5
391 suppliers
$16.30/1g

Yield:2052-07-5 91 %Chromat.

Reaction Conditions:

with C₃₆H₃₆Cl₂Fe₂NPPd;sodium carbonate in N,N-dimethyl-formamide at 100; for 18 h;Inert atmosphere;Schlenk technique;Suzuki-Miyaura Coupling;

Steps:

5.General procedure for the Suzuki-Miyaura cross-coupling reactions
General procedure: In a Schlenk tube under N 2 1.0 mmol of aryl bromide, 1.0 mmol of aryl boronic acid, and 0.5 or 0.25% mol of catalyst in 5 mL of DMF were introduced into a Schlenk tube. The tube was charged with a magnetic stir bar and base (Na 2 CO 3 , 2 mmol), and sealed, then fully immersed in a 100 °C oil bath. After 18 hrs, the mix- ture was cooled to room temperature. Water was added (20 mL). The white suspension was extracted with dichloromethane (3 ×50 mL). The organic phase was washed once again with water, sepa- rated and treated with anhydrous MgSO 4 , filtered, and analyzed by gas chromatography (GC-MS). The results presented are the aver- age of two runs.

References:

Anzaldo, Bertin;Gavi?o, Ruben;Gutiérrez, René;Sharma, Pankaj;Toscano, Alfredo R.;Villamizar C, Claudia P. [Journal of Organometallic Chemistry,2020,vol. 929,art. no. 121577]