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ChemicalBook CAS DataBase List 2-BROMO-6-FLUOROANILINE
65896-11-9

2-BROMO-6-FLUOROANILINE synthesis

4synthesis methods
-

Yield:65896-11-9 86%

Reaction Conditions:

Stage #1:2-bromo-6-fluorobenzoic acid with sulfuric acid at 60; for 1.5 h;
Stage #2: with sodium azide at 20; for 42 h;Schmidt rearrangement;
Stage #3: with ammonium hydroxide at 0;

References:

Morrison, Matthew D.;Hanthorn, Jason J.;Pratt, Derek A. [Organic Letters,2009,vol. 11,# 5,p. 1051 - 1054] Location in patent:supporting information; experimental part

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