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ChemicalBook CAS DataBase List 2-AMINO-3-CYANO-5-METHYLPYRAZINE 1-OXIDE
19994-56-0

2-AMINO-3-CYANO-5-METHYLPYRAZINE 1-OXIDE synthesis

3synthesis methods
-

Yield:19994-56-0 84.5%

Reaction Conditions:

with 2-oxopropanal-1-oxime in isopropanol at 25; for 12 h;

Steps:

27.1 Step 1:

Dissolve aminomalonylbutyl cyanide terephthalate 27a (2.02 g, 8.04 mmol) and 2-oxopropanal-1-oxime (700 mg, 8.04 mmol) in isopropanol (15 mL).The reaction was stirred at 25 degrees Celsius for 12 hours.After the reaction was completed, compound 27b (1.02 g, 84.5% yield) was obtained by filtration.

References:

WO2022/199611,2022,A1 Location in patent:Page/Page column 43

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