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ChemicalBook CAS DataBase List 2,6-Dichlorobenzoxazole
3621-82-7

2,6-Dichlorobenzoxazole synthesis

7synthesis methods
-

Yield:3621-82-7 95.2%

Reaction Conditions:

with iron(III) chloride;phosphorus pentachloride in toluene at 60; for 0.5 h;Temperature;Reagent/catalyst;

Steps:

1-4 Example 1: A preparation method of high yield 2,6-dichlorobenzoxazole, the operation is as follows
In a 500 ml three-necked flask, 250 ml of toluene was added, 0.1 mol of 6-chlorobenzoxazolone, 25 g of phosphorus pentachloride, 0.5 g of polyphosphoric acid and 0.5 g of ferric chloride were added, and the mixture was heated to 60 °C with stirring. After stirring for 0.5 h,After the post-treatment, the product had a content of 2,6-dichlorobenzoxazole of 98.5% and a yield of 95.2 %

References:

Anhui Feng Le Agrochemical Co., Ltd.;Zhou Kanglun;Su Chaohui;Shi Yimin CN109761928, 2019, A Location in patent:Paragraph 0009; 0016-0023

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