2,4-DIMETHYLBENZYL BROMIDE synthesis
- Product Name:2,4-DIMETHYLBENZYL BROMIDE
- CAS Number:78831-87-5
- Molecular formula:C9H11Br
- Molecular Weight:199.09
16308-92-2
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78831-87-5
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Yield: 100%
Reaction Conditions:
with phosphorus tribromide in di-isopropyl ether at 0 - 35; for 1 h;
Steps:
60
Reference Example 60 1-(bromomethyl)-2,4-dimethylbenzene To a solution (100 mL) of (2,4-dimethylphenyl)methanol (10.77 g) obtained in Reference Example 58 in diisopropyl ether was added phosphorus tribromide (4.90 mL) at 0°C, and the reaction mixture was stirred at room temperature for 1 hr. Water was added to the reaction mixture and the mixture was extracted with ethyl acetate. The extract was washed twice with water, a saturated aqueous sodium hydrogen carbonate solution and saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give the title compound as a colorless oil (yield 15.5g, yield quantitative). 1H-NMR (CDCl3) δ: 2.30 (3H, s), 2.37 (3H, s), 4.50 (2H, s), 6.96-6.99 (2H, m), 7.17-7.19 (1H, m).
References:
Location in patent:Page/Page column 45
50-00-0
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108-38-3
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78831-87-5
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824-55-5
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78831-87-5
69 suppliers
$75.00/1 g