2,4-Dihydroxypyrimidine-5-carboxylic acid synthesis
- Product Name:2,4-Dihydroxypyrimidine-5-carboxylic acid
- CAS Number:23945-44-0
- Molecular formula:C5H4N2O4
- Molecular Weight:156.1
65-71-4
510 suppliers
$5.00/5g
23945-44-0
276 suppliers
$5.00/250mg
Yield:23945-44-0 96.1%
Reaction Conditions:
with dihydrogen peroxide;1-hydroxy-1,2,3-benzotriazine-4(3H)-one in water at 130; for 3 h;Autoclave;Temperature;
Steps:
6
Add 100 g of thymine and 300 mL of water to the autoclave, and add 35 mL of hydrogen peroxide at a concentration of 30%.15 g of 1-hydroxy-1,2,3-benzotriazine-4(3H)-one and 35 g of the catalyst prepared in Example 3, replacing the inside of the autoclave with an oxygen atmosphere, and heating to 130 ° C for 3 h.The reaction solution was cooled, filtered, concentrated, and placed in an ice-water mixture to cool.150 g of a white solid was precipitated, the yield was 96.1%, and the purity was 99.3%.
References:
Zhengzhou Gaike Technology Co., Ltd.;Guo Libing;Fan Liming CN108341785, 2018, A Location in patent:Paragraph 0014-0020
1195-08-0
148 suppliers
$23.00/100mg
23945-44-0
276 suppliers
$5.00/250mg
4433-40-3
214 suppliers
$6.00/250mg
23945-44-0
276 suppliers
$5.00/250mg
110821-07-3
25 suppliers
$90.00/1g
23945-44-0
276 suppliers
$5.00/250mg
65-71-4
510 suppliers
$5.00/5g
1195-08-0
148 suppliers
$23.00/100mg
23945-44-0
276 suppliers
$5.00/250mg